Jack Andraka. You may not have heard of his name, but you certainly should.
In this world where social media ‘influencers’ are promoted for their style of clothing or the way they look, only few people like Jack are celebrated like they actually should be.
At the tender age of just 15, Jack Andraka invented his own medical breakthrough that has the potential to save a huge number of lives.
He created a device with the ability to detect pancreatic cancer far earlier than had previously been possible, and that could really draw the difference between life and death for a large portion of sufferers.
The young inventor, from Crownsville, Maryland, was motivated to work on his project after witnessing the death of a close friend from pancreatic cancer. He understood that much of the issue lay in the fact that late-stage pancreatic cancer detection is literally a death sentence, while when detected early it is possible for other people to survive it.
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And so Andraka started his journey to figure out a way of detecting the cancer earlier. During his research, he found that the most up-to-date method of detection was 60 years old. This, surely, was unacceptable.
So he worked to invent a method that is, according to reports, 168 times faster, 26,000 less expensive, and 400 times more sensitive. Oh, and it’s 100% accurate, compared to the 70% the older method promised.
“I made the discovery with a laptop, a smartphone, and some online searches,” he said, for National Geographic.
Andraka’s first step was to isolate a molecule as a “bio marker” of pancreatic cancer, one that happened during the early stages of the disease. The name of the protein is mesothelin, and he had the ability to locate it on his 4,000th try.
At the same time, by coincidence, Andraka’s school science class was discussing antibodies – molecules that bind with one specific protein.
It was a combination of these two things that he got his idea of finding an antibody that would bind with his mesothelin bio marker.
Keeping this in mind, Andraka established a theory that by interweaving antibodies with a network of nanotubes (cylinders that are one-50,000th the diameter of a human hair), a person could potentially detect higher levels of mesothelin present in blood samples from early-stage pancreatic cancer patients.
Taking things to a whole another level
It was time for Andraka to test his theory, though of course this wasn’t something that could simply be done anywhere. He drafted a budget, compiled a list of necessary materials, a time line and a procedure. He sent of all of this information to 200 researchers in the hope that at least one of them would be kind to give him lab space.
199 refused him. Luckily, one pathologist and pancreatic cancer researcher at John Hopkins School of Medicine, Anirban Maitra, said yes.
After exhausting efforts and numerous times of trying and failing, Jack Andraka invented a small device that could detect cancer early and is, reportedly, 100%
accurate. It’s still preliminary, but drug companies are interested, and word is spreading Andraka believes his device could detect any disease.
He told National Geographic: “By changing the antibody, this sensor could detect biomarkers for Alzheimer’s, heart disease, HIV/AIDS, malaria, and other cancers.
“I couldn’t save my friend who died of pancreatic cancer, but I hope I’ve discovered something that means other families won’t have to face similar struggles.”
Way to go, Jack! What an inspiring young genius, and what a marvelous thing you’ve done.
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